The increasing prevalence of the obesity epidemic worldwide is a major threat to global health in terms of morbidity and mortality. Obesity is associated with a variety of health problems, including diabetes, cardiovascular disease, reproductive disorders, osteoarthritis, gallstones, nonalcoholic fatty liver disease, respiratory disease, and, according to studies, some types of cancer. . The problem of obesity and smoking can be followed for public health as the cause of cancer. Increased BMI has been shown to increase the risk of some types of cancer. , such as esophageal adenocarcinoma, melanoma, leukemia, multiple myeloma, non-Hodgkin's lymphoma and colon cancer. , thyroid, endometrium, kidney, gall bladder, rectum, etc. including breast and pancreatic cancers.
Why are obese people prone to cancer? Biological mechanisms seem to link obesity to many types of cancer. are several factors and involve a network of metabolic factors and the immune system. Multiple mechanisms by which obesity stimulates or promotes tumorigenesis. , including insulin resistance and resulting chronic hyperinsulinemia, increased availability of steroid hormones, high consumption of foods rich in fat, and lack of physical activity.